atrial fibrosis

基本解释

Fibrosis of atrial myocytes may be involved in the occurrence and maintenance of AF.
心房肌的纤维化与房颤的发生及维持有关。
Hypertensive patients have a higher incidence of atrial arrhythmia which might be related to atrial enlargement or fibrosis.
高血压患者有较高心律失常的发生率，房性心律失常可能与左房扩大或心房纤维化有关。
Congestie heart failure produces atrial interstitial fibrosis, which promotes arrhythmogenesis by interfering with atrial conduction properties.
充血性心力衰竭所致的心房间质纤维化，通过影响心房传导来促进心律失常的发生。

心房纤维化
TGFβ1 and HGF could respectively promote and inhibit proliferation of atrial fibroblast;expression of CTGF,α-SMA; secretion of collagen I ,MMP-2;and atrial fibrosis.
TGFβ1和HGF分别通过促进和抑制心房成纤维细胞增殖,上调和下调细胞CTGF、α-SMA表达及胶原和MMP-2分泌,促进和抑制心房纤维化。