Acrab

常见例句

• No deletion or point mutation in acrAB gene were found in Mar and susceptible clinical Escherichia coli isolates.
  多重耐药株以及敏感株acrAB基因扩增产物无点突变和缺失。
• Chromosomally mediated multidrug resistance in Salmonella typhimurium is generally attributed to the overexpression of the acrAB locus and the mutation in topoisomerase genes.
  AcrAB外流泵系统的过度表达和拓扑异构酶基因突变是导致鼠伤寒沙门菌产生多重耐药性 (MAR)的重要原因。
• Methods Accumulation of ciprofloxacin in clinical isolates of Escherichia coli was measured by fluorometry, and acrAB gene was identified by PCR and Southern blot.
  方法 应用荧光法测定临床分离大肠杆菌对环丙沙星的主动外排功能 ; PCR及Southernblot测定主动外排系统AcrAB结构基因acrAB ;
• There was high degree of homology in nucleotide sequence between the PCR expandedATCC 10031 acrAB gene sections and the corresponding ones in Escherichia coli.
  PCR扩增的 ATCC 10031的 acrAB基因片段同大肠埃希菌acrAB基因相应片段,在核苷 序列上具有很高的同源性。
• The acrAB locus encode the efflux pump AcrAB,which confers multidrug tolerance,controlled by the regulon marRAB. Mutation in the gyrase and topoisomerase IV lead to fluoroquinolones resistance, mainly arise in gyrA and parC genes.
  AcrAB外流泵系统的合成有多重耐药调节子 (marRAB)调控 ,AcrAB与多种抗生素的耐药有关。 拓扑异构酶 (topoisomerase)的突变主要与氟喹诺酮类药物的耐药性有关 ,突变主要发生在gyrA ,parC基因上
• It suggested that the level of resistance of isolates would be related to selecting pressure of fluoroquinolones and induced gene mutations of DNase and topoisomerase IV could not activate AcrAB efflux pump system.
  提示临床分离的鸡大肠杆菌O 78的耐药水平与喹诺酮类药物的选择性压力有关,它诱导了DNA旋转酶和拓扑异构酶IV的基因突变,可能不能激活A crAB外输泵。
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