irrevocable

1. ADJ If a decision, action, or change is irrevocable, it cannot be changed or reversed. 不可改變的[正式]

He said the decision was irrevocable. 他說過這項決定是不可改變的。

2. irrevocablyADV 不可改變地

My relationships with friends have been irrevocably altered by their reactions to my illness. 由於朋友們對我的病情所做出的反應，我和他們的關系已經徹底改變了。